IVF Historical Perspective

The first successful human birth from in vitro fertilization (IVF) occurred on July 25, 1978 in Great Britain. On December 28, 1981, the first baby conceived through IVF was born in the United States, in Norfolk, Virginia. Since that time, IVF and related technologies have achieved a prominent niche in the clinical management of infertility. In 1996 in the United States, 300 clinics reported initiating 44,647 IVF cycles, 3,768 donor oocyte cycles and 688 cycles of ART for host uterus. A total of 14,702 deliveries were reported. Worldwide over 100,000 children have been born. The major advances in the field of ART are summarized below:

1944 1st IVF attempt
1955 Successful in vitro fertilization of a human oocyte
1958 Gonadotropins extracted from human pituitary glands
1964 Isolation of urinary menopausal gonadotropins
1968 Laparoscopic oocyte retrieval
1976 1st human IVF pregnancy (ectopic)
1978 Birth of Louise Brown in Lancashire, England
1980’s Development of gonadotropin releasing hormone agonists
1981 Birth of Elizabeth Carr in Norfolk, Virginia
1985 Transvaginal oocyte retrieval with sonographic guidance
1990 Assisted hatching
1990 Development of gonadotropin releasing antagonists
1993 Intracytoplasmic sperm injection
1996 Blastocyst transfer
1998 Clinical trials using gonadotropin releasing antagonists

Physician Resources

Sorry, the comment form is closed at this time.